Three cool new advancements in drug delivery

drug delivery bioedical engineering
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The way we deliver drugs into our bodies has come a long way  thanks to advances in biology, medicine and engineering. Here are just three cool recent examples

1. Robotic pills

Engineers at the University of Wollongong, led by Professor Gursel Alici, are developing pills that can be remotely ‘driven’ through a patient’s body to diagnose and treat gastrointestinal tract diseases. Currently, examining the gut means inserting a long tube with a camera (two guesses where it’s inserted?). Instead, this ‘robotic’ capsule is wireless and driven using  a system of magnets – enabling the patient to go on with their day while their insides are screened! It could also be used to deliver drugs to treat disease at the site. And the capsule may even be able to take biopsies (tissue samples) one day.

2. Micro-submarines

Cancer treatments might one day involve tiny, self-propelled ‘micro-submarines’ powered by ‘nano-motors’ delivering drugs directly to affected organs, thanks to research from chemical and biomedical engineers at UNSW. The engineers developed ‘submarine-like’ micrometre-sized metallic particles that take advantage of variations in biological environments, such as different levels of acidity, to automatically navigate inside the body. One ‘capsule’ swallowed by a patient could contain millions of micro-submarines, each of which could contain millions of drug molecules. This means the drugs could be delivered straight into a cell, or the site of a cancer. This is great news for reducing the side effects cancer patients can experience from drugs used in chemotherapy, for example.

3. Good vibrations

In 2016, experts at RMIT University in Melbourne created a new type of ‘soundwave’ using electricity to create vibrations, which are used to turn liquid into a spray. “It’s basically ‘yelling’ at the liquid so it vibrates, breaking it down into vapour,” explains lead researcher and engineering lecturer Dr Amgad Rezk. Researchers have already used it in a new inhaler to deliver needle-free vaccines. The new soundwave could even be used to inhale stem cells (which can turn into different types of cells with specific functions) straight into the lungs to repair lung tissue.

This article originally appeared in Careers with STEM: Engineering 2019

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Gemma Chilton

Author: Gemma Chilton

Gemma is the Managing Editor of Careers with STEM magazine. She has previously worked as Digital Managing Editor at Australian Geographic and a staff writer at Cosmos science magazine.


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